NFL WEEK 6 PICKS: Tampa Bay – Buc Derek Carr-less Saints

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Lines are from Covers.com and home teams are in CAP.

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San Francisco -3.5 over SEATTLE

The 49ers picked up a much-needed win against a division rival — even if they spent some time trying to blow it away in the second half — but suffered even more injuries on the way back to the Super Bowl.

Jacksonville +2.5 over CHICAGO in London

Although the Bears are listed as hosts, the Jaguars should actually feel at home in London after winning both games in the UK last year. The tape still doesn't fully match Bears rookie Caleb Williams' recent performance.

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Tampa Bay -3.5 over NEW ORLEANS

Not only have the Saints proven themselves offensively after an extremely hot start to the season, but Derek Carr is now expected to miss several weeks with an injury. The Bucks need to take advantage of his absence here.

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GREEN BAY -5 over Arizona

While Kyler Murray can look electric at times, the Cardinals offense hasn't been that hot and ranks slightly above average in DVOA. The difference is that Arizona's defense is among the worst in the league and the Packers should be able to go to town.

TENNESSEE -1 over Indianapolis

While the Colts defense is improving, this is not the week to support them. Anthony Richardson looks ready to return from injury. ​​Are we sure this is good? A little practice with Joe Flacco can go a long way in the long run.

PHILADELPHIA -9 over Cleveland

We hate to play against a big underdog that has so many coverages and even wins outright, but no, we just can't put Deshaun Watson on the road against a decent defense. Also, watch out because it looks like AJ Brown and DeVonta Smith will be back.

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NEW ENGLAND +7 over Houston

It's time for Drake Maye! Jacoby Brissett looked terrible and a slight addition at QB should be enough for the hosts to beat.

Washington +6.5 over BALTIMORE

While we're certainly not betting on the Ravens winning this game outright, this line is big enough for the Commanders to sneak in a cover through the back door.

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DENVER +3 over LA Chargers

The Chargers are on their bye, which has certainly helped their walking wounded recover, but the Broncos have been a surprise so far. Denver's defense looks good and will at least make this game a grind. We would love to earn points as a pet dog.

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Pittsburgh -3 over LAS VEGAS

Do the Raiders really think that switching to Aiden O'Connell at QB the week they face the Steelers defense will make a difference? And with Christian Wilkins on infrared, Vegas' defense will be easier to carve up.

Atlanta -6 over CAROLINA

We'd love to pick on the Panthers like a dog, but the numbers are really starting to back up the fact that Kirk Cousins ​​and the Falcons offense is improving week over week. Taking matters up with Andy Dalton only got Carolina so far.

Detroit -3 over DALLAS

The Cowboys suffered a major upset on the road Sunday night in Pittsburgh and will need to come back immediately and face another solid team. When these teams met last year, the Lions were on the wrong side of a terrible refereeing decision and will certainly be looking for revenge this time.

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Cincinnati -3.5 vs. NEW YORK GIANTS

The biggest concern is the Bengals' defense. But any fear that the Giants might be able to take advantage of it is tempered by the memory of Daniel Jones, who is on the other side of the coin.

NEW YORK JETS +2.5 over Buffalo

Oh hey, it's the new coach! Remember that last year it was the Jets who beat the Bills in the first game in New York, and Aaron Rodgers strained his Achilles after four games.

Last week: 6-7-1

This season: 35-41-2

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